Why is Deinococcus radiodurans so resistant to ionizing radiation?
| Autor: | Ashlee M. Earl, John R. Battista, Mie-Jung Park |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
DNA Replication
DNA Bacterial Recombination Genetic Microbiology (medical) Mutation γ radiation biology DNA repair DNA damage Deinococcus radiodurans biology.organism_classification medicine.disease_cause Radiation Tolerance Microbiology Ionizing radiation Cell biology Gram-Positive Cocci Infectious Diseases DNA degradation Gamma Rays Virology medicine Genome Bacterial DNA Damage |
| Zdroj: | Trends in Microbiology. 7:362-365 |
| ISSN: | 0966-842X |
| DOI: | 10.1016/s0966-842x(99)01566-8 |
| Popis: | When exponential-phase cultures of Deinococcus radiodurans are exposed to a 5000-Gray dose of γ radiation, individual cells suffer massive DNA damage. Despite this insult to their genetic integrity, these cells survive without loss of viability or evidence of mutation, repairing the damage by as-yet-poorly-understood mechanisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect