Chitosan nanoparticles containing Physalis alkekengi-L extract:preparation, optimization and their antioxidant activity
| Autor: | Abouzar Bagheri, Reza Mahmoudi, Farhang Aliakbari, Sajad Afrouz, Zeinab Salehpour, Hossein Mohammad-Beigi, Hassan Bardania, Mohsen Alipour, Behnam Hajipour Verdom, Maryam Tajali Ardakani |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Materials science
Antioxidant medicine.medical_treatment chitosan nanoparticles antioxidant activity HELA 02 engineering and technology 010402 general chemistry 01 natural sciences NANOENCAPSULATION VAR. FRANCHETII MAST. MAKINO medicine stability of extract General Materials Science Food science Response surface methodology Physalis alkekengi L FRUITS biology STABILITY Chitosan nanoparticles IN-VITRO 021001 nanoscience & nanotechnology biology.organism_classification Physalis alkekengi-L 0104 chemical sciences Antioxidant capacity Mechanics of Materials Physalis Medicinal herbs 0210 nano-technology |
| Zdroj: | Mahmoudi, R, Ardakani, M T, Verdom, B H, Bagheri, A, Mohammad-Beigi, H, Aliakbari, F, Salehpour, Z, Alipour, M, Afrouz, S & Bardania, H 2019, ' Chitosan nanoparticles containing Physalis alkekengi-L extract : preparation, optimization and their antioxidant activity ', Bulletin of Materials Science, vol. 42, no. 3, 131 . https://doi.org/10.1007/s12034-019-1815-3 Mahmoudi, R, Tajali Ardakan, M, Hajipour Verdom, B, Bagheri, A, Mohammad-Beigi, H, Aliakbari, F, Salehpour, Z, Alipour, M, Afrouz, S & Bardania, H 2019, ' Chitosan nanoparticles containing Physalis alkekengi-L extract: preparation, optimization and their antioxidant activity ' Bulletin of Materials Science, vol. 42, no. 131 . |
| DOI: | 10.1007/s12034-019-1815-3 |
| Popis: | Physalis alkekengi-L is a medicinal herb with a high antioxidant capacity. It is used to treat various diseases. In this study, encapsulation of the hydro-alcoholic extract of P. alkekengi-L into chitosan nanoparticles (CNPs) was optimized by using response surface methodology, and its antioxidant capacity and anticancer activity were investigated. The results of the antioxidant capacity evaluation showed that the antioxidant activity of the chitosan nanoparticles containing extract did not significantly decrease by increasing the time of storage (over a 12 day period) as compared to that of un-encapsulated extracts. In conclusion, CNPs can be used to encapsulate and improve the stability of P. alkekengi-L extract and its antioxidantproperties. |
| Databáze: | OpenAIRE |
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