Deep Sequential Feature Learning in Clinical Image Classification of Infectious Keratitis

Autor: Qiang Zhu, Wen-jia Xie, Runping Duan, Siliang Tang, Yu-Feng Yao, Zhengqing Fang, Fei Wu, Ming Kong, Ye-sheng Xu, Yuxiao Lin
Rok vydání: 2021
Předmět:
FOS: Computer and information sciences
medicine.medical_specialty
Environmental Engineering
genetic structures
General Computer Science
Computer Vision and Pattern Recognition (cs.CV)
Materials Science (miscellaneous)
General Chemical Engineering
Computer Science - Computer Vision and Pattern Recognition
Energy Engineering and Power Technology
02 engineering and technology
Infectious Keratitis
010402 general chemistry
01 natural sciences
Corneal disease
Ophthalmology
Cornea
Machine learning
Long short-term memory
FOS: Electrical engineering
electronic engineering
information engineering

medicine
Contextual image classification
Corneal Damage
business.industry
Corneal Diseases
Image and Video Processing (eess.IV)
Disease progression
General Engineering
Deep learning
Electrical Engineering and Systems Science - Image and Video Processing
Engineering (General). Civil engineering (General)
021001 nanoscience & nanotechnology
eye diseases
0104 chemical sciences
medicine.anatomical_structure
sense organs
TA1-2040
0210 nano-technology
business
Sequential features
Feature learning
Zdroj: Engineering, Vol 7, Iss 7, Pp 1002-1010 (2021)
ISSN: 2095-8099
Popis: Infectious keratitis is the most common entities of corneal diseases, in which pathogen grows in the cornea leading to inflammation and destruction of the corneal tissues. Infectious keratitis is a medical emergency, for which a rapid and accurate diagnosis is needed for speedy initiation of prompt and precise treatment to halt the disease progress and to limit the extent of corneal damage; otherwise it may develop sight-threatening and even eye-globe-threatening condition. In this paper, we propose a sequential-level deep learning model to effectively discriminate the distinction and subtlety of infectious corneal disease via the classification of clinical images. In this approach, we devise an appropriate mechanism to preserve the spatial structures of clinical images and disentangle the informative features for clinical image classification of infectious keratitis. In competition with 421 ophthalmologists, the performance of the proposed sequential-level deep model achieved 80.00% diagnostic accuracy, far better than the 49.27% diagnostic accuracy achieved by ophthalmologists over 120 test images.
Comment: Accepted by Engineering
Databáze: OpenAIRE