The three-hybrid genetic composition of an Ecuadorian population using AIMs-InDels compared with autosomes, mitochondrial DNA and Y chromosome data
| Autor: | Paola E. Leone, Santiago Guerrero, M. Vela, Verónica Yumiceba, Ana Karina Zambrano, Anibal Gaviria, Andrés López-Cortés, Santiago Cobos-Navarrete, Patricia Guevara-Ramírez, César Paz-y-Miño, Cristina Rodríguez-Pollit, Isaac Armendáriz-Castillo, Carmen Gruezo, Jennyfer M. García-Cárdenas, Gisella Fiallos, Andy Pérez-Villa |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male Mitochondrial DNA Population lcsh:Medicine Biology Y chromosome DNA Mitochondrial Article 03 medical and health sciences 0302 clinical medicine INDEL Mutation parasitic diseases Ethnicity Humans lcsh:Science Indel education Chromosome Aberrations education.field_of_study Multidisciplinary Autosome Chromosomes Human Y lcsh:R Haplotype Racial Groups DNA Fingerprinting 030104 developmental biology Genetics Population DNA profiling Haplotypes Evolutionary biology lcsh:Q Female Structural variation Ecuador 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019) |
| ISSN: | 2045-2322 |
| Popis: | The history of Ecuador was marked by the arrival of Europeans with Africans, resulting in the mixture of Native Americans with Africans and Europeans. The present study contributes to the knowledge of the Ecuadorian mestizo population by offering information about ancestry and ethnic heterogeneity. Forty-six AIM-InDels (Ancestry Informative Insertion/Deletion Markers) were used to obtain information on 240 Ecuadorian individuals from three regions (Amazonia, the Highlands, and the Coast). As a result, the population involved a significant contribution from Native Americans (values up to 51%), followed by Europeans (values up to 33%) and Africans (values up to 13%). Furthermore, we compared the data obtained with nine previously reported scientific articles on autosomal, mitochondrial DNA and Y chromosomes. The admixture results correspond to Ecuador’s historical background and vary slightly between regions. |
| Databáze: | OpenAIRE |
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