Low Serum Magnesium Levels and Its Association with High Blood Pressure in Children
| Autor: | María Elena Haro Acosta, Celsa López Campos, Martha Rodríguez-Morán, Ricardo Pérez Fuentes, José de Jesús Peralta Romero, Irma Isordia Salas, Guadalupe Ruiz Vivanco, Héctor Rafael Sánchez Nuncio, María Luisa Pizano-Zárate, Ana María Salinas Martínez, María de Socorro Romero Figueroa, Eulalia Garrido Magaña, Rosa Ortega Cortés, Eduardo Almeida Gutiérrez, Cecilia Colunga Rodríguez, Maria Elena Y. Furuya Meguro, Andrea Socorro Álvarez Villaseñor, Cruz Mónica López Morales, Brian González Pérez, Ricardo Salas Flores, Mirna Aurea Huerta Orea, Laura Hermila de la Garza, Ricardo Jorge Hernández Herrera, Niels H. Wacher, Gloria Patricia Sosa Bustamante, Miguel Angel Villasís Keever, Gabriela Escudero Lourdes, Haydé Rosas Vargas, Antonio Pineda Carranza, Miguel Cruz López, Luis E. Simental-Mendía, Gabriela Borrayo Sánchez, Francisco González Salazar, Anel Gómez García, José Ramón Paniagua Sierra, Mardia López Alarcón, Carolina Elizabeth Medina Escobedo, Fernando Guerrero-Romero, Sonia Lazcano, Flor Araceli Nava Ayala, Ma. Guadalupe Ruíz Charles, María Eugenia Galván Plata, Gabriela Hernández-Ronquillo, Jesus Nares Cisneros, Rafael Mondragón-González, Rita A. Gómez-Díaz, Marco Antonio León Mazón, Martha I. Dávila Rodríguez, María Valeria Jiménez Baéz, Norma Alicia Sánchez Hernández |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Cross-sectional study Blood Pressure Type 2 diabetes 030204 cardiovascular system & hematology Gastroenterology Prehypertension Hypomagnesemia 03 medical and health sciences 0302 clinical medicine Risk Factors 030225 pediatrics Internal medicine medicine Prevalence Humans Magnesium Child Mexico Endocrine disease business.industry medicine.disease Impaired fasting glucose Blood pressure Endocrinology Cross-Sectional Studies Logistic Models Pediatrics Perinatology and Child Health Hypertension Female business Body mass index |
| Zdroj: | The Journal of pediatrics. 168 |
| ISSN: | 1097-6833 |
| Popis: | To evaluate the association of hypomagnesemia with prehypertension (preHTN) and hypertension in children.A total of 3954 apparently healthy Mexican children were enrolled in a cross-sectional study. Exclusion criteria were type 2 diabetes; hepatic, renal, or endocrine disease; impaired fasting glucose; chronic diarrhea; and intake of vitamins or magnesium supplements in the previous 6 months. preHTN was defined by systolic and/or diastolic blood pressure ≥90th to95th percentile and hypertension by systolic and/or diastolic blood pressure ≥95th percentile, according to age, sex, and height percentile. Hypomagnesemia was defined by serum magnesium concentration1.8 mg/dL (0.74 mmol/L). To control for potential sources of bias related to age, participants were allocated into 2 groups, aged 6-10 years and 11-15 years.The prevalence of preHTN and hypertension was 12.2% and 6.4%, respectively, in children aged 6-10 years and 13.9% and 10.6% in those aged 11-15 years. Hypomagnesemia was identified in 59 children with preHTN (27.3%) and 52 (45.6%) with hypertension in the 6-10 year age group, and in 115 children with preHTN (36.0%) and 109 (49.6%) with hypertension in the 11-15 year age group. Adjusted multiple logistic regression analysis showed that in children in both age groups, hypomagnesemia was associated with both preHTN (6-10 years: OR, 2.18, P .0005; 11-15 years: OR, 1.38, P = .018) and hypertension (6-10 years: OR, 4.87, P .0005; 11-15 years: OR, 1.83, P = .0002).Our results indicate that serum magnesium level1.8 mg/dL is significantly associated with preHTN and hypertension in apparently healthy children. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect