Pharmacological studies of Panacis Japonici Rhizoma. I
| Autor: | Junzo Shoji, Hiroshi Saito, Shoji Shibata, Keijiro Takagi, Yien-Mei Lee, Noriko Kondo |
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| Rok vydání: | 1977 |
| Předmět: |
Drug
media_common.quotation_subject Traditional Chinese medicine Pharmacology Mice Increased intestinal motility Drug Discovery medicine Animals Humans Hypnotics and Sedatives Antipyretic Expectorant media_common Analgesics Plants Medicinal Chikusetsusaponin IV Plant Extracts Chemistry Hemodynamics General Chemistry General Medicine Chikusetsusaponin III Rats Chikusetsusaponin V Muscle Contraction medicine.drug |
| Zdroj: | Chemical and Pharmaceutical Bulletin. 25:1017-1025 |
| ISSN: | 1347-5223 0009-2363 |
| DOI: | 10.1248/cpb.25.1017 |
| Popis: | Pharmacological properties attributed to Panacis Japonici Rhizoma (PJR) in Chinese medicine in Japan in terms of its usage as a drug for gastroenteric disorders, antipyretic, antitussive, expectorant and antiinflammatory drug, were studied. Chikusetsusaponin III was especially remarkable as it had antipyretic, antitussive, expectorative and antiedemic activities, increased intestinal motility, and prevented stress ulcers. Chikusetsusaponin IV showed expectorative action, protection against stress ulcers and acceleration of intestinal motility. Chikusetsusaponin V showed antiedemic activity. The substance giving protective effect against gastric secretion was found in the butanol layer but was not recognized in the saponins. Increased effect of intestinal motility was recognized in aqueous extract. |
| Databáze: | OpenAIRE |
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