The Effects of Crossing Porcine Renal Artery Ostia with Various Endovascular Stents
| Autor: | Jonathan Beard, T Whitbread, I Palmer, P.A Gaines, P.C Birch, R.D Start |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Aortography Swine medicine.medical_treatment Blood Pressure Aortic aneurysm chemistry.chemical_compound Renal Artery Endovascular repair medicine.artery Intravascular ultrasound Occlusion medicine Animals cardiovascular diseases Renal artery Medicine(all) Creatinine Aorta medicine.diagnostic_test business.industry Stent Equipment Design equipment and supplies medicine.disease Surgery Radiography Renal arteries surgical procedures operative chemistry Evaluation Studies as Topic Microscopy Electron Scanning cardiovascular system Female Stents Radiology Cardiology and Cardiovascular Medicine business Aortic Aneurysm Abdominal |
| Zdroj: | European Journal of Vascular and Endovascular Surgery. 17:185-190 |
| ISSN: | 1078-5884 |
| DOI: | 10.1053/ejvs.1998.0672 |
| Popis: | Objectives to compare the effects of crossing renal artery ostia with various stents. Methods the renal artery ostia of 24 large white pigs were covered with a Wallstent® (nine ostia), a Palmaz® stent (nine ostia) and a Memotherm® stent (13 ostia). After an interval of 6–15 weeks, aortography, renal pressure and blood samples were performed and the pigs then sacrificed for histological examination. Results histological examination revealed an organised collagen matrix with endothelial cells covering the struts in contact with the aorta. This occurred with all stents but was most organised with the Wallstent. This matrix did not involve the renal artery ostia crossed by Wallstents, but in one Palmaz stent and in 12/13 Memotherm stents, a disorganised acellular matrix caused partial ostial occlusion. There was no mean fall in renal artery pressure but traces were damped in 8/13 cases of partial occlusion. There was a rise in serum creatinine in two cases using the Palmaz stent. Conclusions covering renal arteries with the Wallstent appears to be safe in the short-term. Placement of stents with larger struts across renal arteries will require imaging methods, such as intravascular ultrasound (IVUS) to ensure that the ostia are not obstructed. |
| Databáze: | OpenAIRE |
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