Antibacterial, anti-biofilm and anticancer potentials of green synthesized silver nanoparticles using benzoin gum (Styrax benzoin) extract
| Autor: | Juan Du, Hina Singh, Tae-Hoo Yi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Silver
Metal Nanoparticles Antineoplastic Agents Bioengineering 02 engineering and technology 010402 general chemistry 01 natural sciences Styrax Silver nanoparticle Mice Dynamic light scattering Neoplasms Escherichia coli Zeta potential Animals Humans Organic chemistry Fourier transform infrared spectroscopy Cytotoxicity biology Plant Extracts Chemistry General Medicine Styrax benzoin 021001 nanoscience & nanotechnology Antimicrobial biology.organism_classification Anti-Bacterial Agents 0104 chemical sciences HaCaT Biofilms 0210 nano-technology HeLa Cells Biotechnology Nuclear chemistry |
| Zdroj: | Bioprocess and Biosystems Engineering. 39:1923-1931 |
| ISSN: | 1615-7605 1615-7591 |
| DOI: | 10.1007/s00449-016-1666-x |
| Popis: | This study described a simple and green approach for the synthesis of silver nanoparticles (AgNPs) employing benzoin gum water extract as a reducing and capping agent and their applications. The AgNPs were characterized by ultraviolet-visible spectrophotometer, X-ray diffraction pattern, field emission transmission electron microscopy, dynamic light scattering, zeta potential and fourier transform infrared spectroscopy. The AgNPs showed promising antimicrobial activity against various pathogens (Gram-negative, Gram-positive and fungus) and possessed high free radical scavenging activity (104.5 ± 7.21 % at 1 mg/ml). In addition, the AgNPs exhibited strong cytotoxicity towards human cervical cancer and human lung cancer cells as compared to the normal mouse macrophage cells. Moreover, the AgNPs possessed anti-biofilm activity against Escherichia coli, and compatibility to human keratinocyte HaCaT cells, which suggests the use of dressing with the AgNPs in chronic wound treatment. Therefore, AgNPs synthesized by benzoin gum extract are comparatively green and may have broad spectrum potential application in biomedicine. |
| Databáze: | OpenAIRE |
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