Secondary hyperparathyroidism prevalence and prognostic role in elderly males with heart failure
| Autor: | Vera Popovic, Zoran Radojicic, Hans-Dirk Düngen, Natasa Cvetinovic, Biljana Bozic, Goran Loncar, Wolfram Doehner, Biljana Putnikovic, Tobias Daniel Trippel, Mitja Lainscak, S. Von Haehling |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Renal function 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Gastroenterology 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine Prevalence Vitamin D and neurology Humans Medicine Survival analysis Aged Heart Failure Hyperparathyroidism Ejection fraction Proportional hazards model business.industry Middle Aged Prognosis medicine.disease Survival Rate ROC Curve Heart failure Quality of Life Cardiology Hyperparathyroidism Secondary Secondary hyperparathyroidism business Serbia Biomarkers |
| Zdroj: | Journal of Endocrinological Investigation. 40:297-304 |
| ISSN: | 1720-8386 |
| DOI: | 10.1007/s40618-016-0561-2 |
| Popis: | Evaluation of secondary hyperparathyroidism (SHPT) and its prognostic impact on all-cause mortality in elderly males with heart failure (HF). Seventy three males (67 ± 7 years old) with systolic HF were included. Baseline PTH was measured. Patients were grouped according to PTH cut-off levels of 65 pg/ml (>65 pg/ml = SHPT vs. normal PTH). All-cause mortality was evaluated at 6-year follow-up. SHPT was diagnosed in 43 (59 %) patients. They were more severe compared to the patients with normal PTH regarding NYHA functional class (2.4 ± 0.5 vs. 2.1 ± 0.2, p = 0.001), quality of life score (34 ± 14 vs. 24 ± 12, p = 0.005), 6-min walking distance (378 ± 79 vs. 446 ± 73 m, p |
| Databáze: | OpenAIRE |
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