Cystoisosporiasis-related human acalculous cholecystitis: the need for increased awareness
| Autor: | Mahmoud Agholi, Elham Aliabadi, Gholamreza Hatam |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty medicine.medical_treatment Isosporiasis corticosteroid therapy H&E stain lcsh:Medicine Cystoisospora belli Gastroenterology Pathology and Forensic Medicine 03 medical and health sciences Immunocompromised Host 0302 clinical medicine Adrenal Cortex Hormones cholecystitis Internal medicine medicine Humans Acalculous Cholecystitis Acquired Immunodeficiency Syndrome biology business.industry Coccidiosis Gallbladder Medical record lcsh:R General Medicine medicine.disease biology.organism_classification Surgery Coccidia AIDS Chronic Acalculous Cholecystitis 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Cholecystitis Cholecystectomy Female business Immunosuppressive Agents |
| Zdroj: | Polish Journal of Pathology, Vol 67, Iss 3, Pp 270-276 (2016) |
| ISSN: | 2084-9869 1233-9687 |
| Popis: | Cholecystitis is one of the common surgical indications affecting human beings in many countries. A variety of infectious agents can be associated with acute or chronic acalculous cholecystitis, especially in HIV/AIDS patients. In this investigation, the authors aim to describe two cases of histologically and molecularly documented cystoisosporiasis (syn. isosporiasis) as the cause of chronic acalculous cholecystitis in two immunodeficient patients. During microscopic examinations of more than 2500 diarrheic patients’ samples, 11 cases of cystoisosporiasis-related recurrent persistent/chronic diarrhea were detected. A review of the medical records of Cystoisospora belli (syn. Isospora belli)-positive patients showed that two of them, i.e. a patient with prolonged corticosteroid therapy and an AIDS patient, several months prior to fecal examinations had undergone cholecystectomy due to acalculous cholecystitis. The study was continued by a review of the histopathological investigation of the recuts prepared from the excised gallbladder tissue sections and stained with hematoxylin and eosin in order to detect a possible specific clinical correlation with cystoisosporiasis. Light microscopic examination revealed the presence of various developmental stages of a coccidial parasite, namely Cystoisospora belli , in both patients’ gallbladder tissue sections. To the best of our knowledge, C. bellii -associated cholecystitis has not been previously reported in a patient with prolonged corticosteroid therapy. |
| Databáze: | OpenAIRE |
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