Oncologic and functional outcomes of transoral CO2 laser cordectomy for early glottic cancer
| Autor: | Kuriko Masuda, Daryl Anne A. del Mundo, Naoki Otsuki, Masanori Teshima, Koichi Morimoto, Ryohei Sasaki, Ken-ichi Nibu, Shinobu Iwaki, Daisuke Miyawaki, Tatsuya Furukawa, Hirotaka Shinomiya |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Glottis medicine.medical_treatment Vocal Cords Speech Acoustics 03 medical and health sciences 0302 clinical medicine Postoperative Complications Larynx preservation medicine Overall survival Humans 030223 otorhinolaryngology Grading (tumors) Laryngeal Neoplasms Aged Neoplasm Staging Aged 80 and over Salvage Therapy Co2 laser Voice Disorders Laryngoscopy business.industry Margins of Excision General Medicine Middle Aged Surgery Radiation therapy Treatment Outcome Otorhinolaryngology Glottic cancer Patient Satisfaction 030220 oncology & carcinogenesis Lasers Gas Cordectomy Salvage surgery Female Laser Therapy Neoplasm Recurrence Local business |
| Zdroj: | Auris, nasus, larynx. 47(2) |
| ISSN: | 1879-1476 |
| Popis: | Objective To investigate the oncological and functional outcomes of the patients treated with transoral CO2 laser cordectomy for early glottic cancer. Patients and methods Fifty-five consecutive patients who underwent CO2 laser cordectomy for early glottic cancer were retrospectively reviewed. Results Overall survival, larynx preservation, and relapse free local control rates were 96%, 100%, and 91%, respectively. Five patients with local recurrences were salvaged with re-cordectomy and/or radiotherapy. In type I cordectomy, VHI-10 consistently improved during postoperative course and VHI-10 at postoperative 12 months was significantly better than preoperative value (2.3 vs. 9.4, p = 0.02). Perceptual grading, MPT, MFR and AC/DC also improved and were better than preoperative values. In type III cordectomy, shimmer at 12 months after cordectomy was significantly better than preoperative value (14.7 vs. 9.3, p = 0.007). Conclusions These results further support the rationale of CO2 cordectomy as initial and salvage surgery for early glottic cancer. |
| Databáze: | OpenAIRE |
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