RNA-sequencing of acute promyelocytic leukemia primary blasts reveals novel molecular biomarkers of early death events

Autor:	Julia Obländer, Wolf-Karsten Hofmann, Eva Lengfelder, Iris Palme, Verena Nowak, Johanna Flach, Uwe Platzbecker, Alexander Streuer, Florian Nolte, Justine Danner, Johann-Christoph Jann, Daniel Nowak, Anna Hecht
Rok vydání:	2020
Předmět:	Acute promyelocytic leukemia Oncology Cancer Research medicine.medical_specialty Population Early death 03 medical and health sciences 0302 clinical medicine Leukemia Promyelocytic Acute hemic and lymphatic diseases Internal medicine Humans Medicine education neoplasms Extracellular Matrix Proteins education.field_of_study Hematology Base Sequence business.industry Mortality rate RNA Prognosis medicine.disease Molecular biomarkers 030220 oncology & carcinogenesis business Biomarkers 030215 immunology
Zdroj:	Leukemia & Lymphoma. 61:3066-3077
ISSN:	1029-2403 1042-8194
DOI:	10.1080/10428194.2020.1797006
Popis:	Although acute promyelocytic leukemia (APL) has evolved to the AML entity with the best prognosis, typical 'early death' (ED) events still account for mortality rates of ∼20% in population-based studies. To investigate this poorly understood issue we performed whole transcriptome analysis of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c623f096e93bd34980c6716007eac9 https://doi.org/10.1080/10428194.2020.1797006 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.