Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers

Autor: de Sá, Nathalia, Teixeira, Sylvia
Rok vydání: 2022
Předmět:
DOI: 10.17605/osf.io/tjnv4
Popis: Different levels of viremia control are observed among HIV-1-infected individuals. Approximately 1% of the HIV-1-seropositive population suppresses viral replication to extremely low or undetectable levels in the absence of antiretroviral therapy and are termed HIV controllers (HICs) or elite controllers (ECs). In this study, we analyzed the distribution of HLA-B and -C, KIR, CCR5 genes, as well as selected SNPs to investigate their impact on the viral control observed in a cohort of Brazilian HICs.
Databáze: OpenAIRE