| Autor: |
J M, Olivares, A, Rodriguez-Morales, J, Diels, M, Povey, A, Jacobs, Z, Zhao, A, Lam, J C, Villalobos Vega, J Alonso, Cuéllar, F J Alberca, de Castro, C Morillo-Velarde, Quintero, J F Román, Martíin, P Tabares, Domínguez, J L Prados, Ojeda, S Sanz, Cortés, F I Mata, Cala, C Gutiérrez, Marín, L Moyano, Castro, M A Haza, Duaso, J Requena, Albarracín, G Narbona, Vergara, A Fernández, Benítez, F Mayoral, Cleries, J M García-Herrera, Pérez-Brian, A Bordallo, Aragón, J C Rodríguez, Navarro, J A Algarra, Biedma, R Bravo, de Pedro, J F Delgado, González, M E Jaén, López, H Díaz, Moreno, J A Soto, López, E Ojeda, Rodríguez, C Martínez, de Hoyos, M Pardilla, Sacristán, M D Molina, Martín, E Martín, Ballesteros, P A Sopelana, Rodríguez, L Fernández, Menéndez, R Santos, Rivas, P, del Pino Cuadrado, J Correas, Lauffer, J J Rodríguez, Solano, J M Fernández, Martínez, F García, Solano, P García-Lamberde, Rodríguez, J A Romero, Rodríguez, T Rodríguez, Cano, M Ducaju, Fortacin, J M Blanco, Lobeiras, J M Piñeiro, Sampedro, A Pérez, Bravo, A Fernández, Pellicer, M D Alonso, López, J Fraga, Liste, M Riobo, Fernández, A Casas, Losada, R Vazquez-Noguerol, Mendez, S Agra, Romero, J J Blanco, Blanco, I Tortajada, Bonaselt, M C García, Mahia, E Ferrer Gómez, del Valle, P Quiroga, Yañez, M Gelabert, Camarasa, J A Barbado, Alonso, G Florez, Mendez, F Doce, Feliz, M A López, Lamela, M Vega, Piñero, P Fuentes, Alvarado, I López, Gómez, P Fadon, Martín, J L Santos, Gómez, A García, López, A Rodríguez, Jiménez, A Escudero, Nafs, N Casas, Barquero, R Fernández-Villamor, Ortiz, J L Velez, Noguera, P Ruiz, Carrasco, J Martín, Muñoz, M Masegoza, Palma, C Marín, Hortelano, L Sánchez, Bonome, J Sánchez, Sevilla, J M Mongil San, Juan, J M García, Ramos, J L Vallejo, Muñoz, J Elorza, Guisasola, L Santamaria, Vazquez, F Campo, Guerras, F J Arrufat, Nebot, F J Baron, Fernández, A L Palomo, Nicolau, R Catala, Subirats, M Messays, Kidias, V Fabregat, Navarro, B Frades, García, F Mejias, del Rosal, T, de Vicente Muñoz, J Año, Ballester, P Malabia, Lieb, A Delgado, Martel, E Roca, Bea, I Grau, Joaquim, F Boatas, Enjuanes, M Bañuelos, Piñol, E Fontova I, Carbonell, R Martín, Muñoz, C Argila, Giribets, L Albages, Sans, A Serrano, Blanco, M Arcega, Felipe, P González, Muñoz, A Pons, Villanueva, M Bernardo, Arroyo, R Coronas, Borri, S Miret, Fallada, M Celma, Merola, E Parellada, Rodon, J R Pigem, Palmes, E Pérez, Martínez, J Matarredona, Catala, A Sandoval, Coca, F Pascual, Ferrandiz, E Ferrandiz, Paya, G Iturri, Caballero, A Franco, Bonet, J Fluvia, Figueras, P Moreno, Pagador, M Medina, Garibo, V Pérez, Camo, C Sanz, Carrillo, C Pelegrin, Valero, F J Caro, Rebollo, J, García Campayo, J M Sala, Sala Ayma, M Martínez, Roig, M A, de Uña Mateos, R García, Bertolin, A Martín, García, F Jiménez, Mazo, J L Galvez, Velasco, L Santa Maria, Pérez, C Jiménez, Casado, J J Mancheño, Barba, M Conde, Diaz, J P Alcon, Rubio, A Soler, Mandoli, A Uson, Herrero, A Rodríguez, Martínez, P Salgado, Serrano, E Nieto, Rodríguez, J Segui, Montesinos, J Ferragud, Macia, A Mateos, Mateos Marcos, J V Pérez-Fuster, Soto, M Verdaguer, Dumont, J Parra, Pagan, V Balanza, Martínez, M, Santiuste de Pablos, C Espinosa, Delgado, M D Martínez, Quiles, F J Manzanera, López, P Pozo, Navarro, A Micol, Torres, F J Martínez, Ingles, J M Salmeron, Arias-Camison, J C López, Manzano, R Villanueva, Peña, G Petersen, Guitarte, H Blasco, Fontecilla, J Barjau, Romero, R Sanz, Gil, J Marín, Lozano, L Donaire, Adanez, I, Zarranz Herrera-Oria, J Pérez, Jiménez, F Carrato, Vaz, O Sanz, García, C Contreras, Anton, R Reixach, Casula, M C Natividad, Hernandez, F Teba, Escabias, J Rodríguez, Torresano, A Huidobro, Pérez-Villamil, L, Estevez, M Aragües, Figuero, A, Muñoz de Morales, J L Rodríguez, Calvin, M Delgado, Criado, V Molina, Rodríguez, E Balbo, Ambrosolio, P M Holgado, Madera, G Ponce, Alfaro, M M Rojas, Vidal, A García, Valtuille, O, Ruiz, G Lucas, Cabornero, M, Echevarria Martínez de Bujo, M J Maicas, Mallen, J Santandreu, Puigros, A Liñana, Martorell, A Clar, Forteza, E Rodríguez, Arrebola, M, Rodríguez de la Torre, C G Anton, Saiz, C, Bardolet I Casas, E Rodríguez, Linde, R, De Arce Cordon, E M Padial, Molina, F J Ruiz, Carazo, J J Muro, Romero, D Vico, Cano, M Soria, Dorado, S Campos, Velazquez, A J Rodríguez, Sánchez, S Ocio, Leon, K Pachas, Sánchez, M Henry, Benitez, A Intxausti, Zugarramurai, M A, Contreras, M, De la Varga González, P Barreiro, Marín, F Gómez, Robina, M Sánchez, García, F J Otero, Pérez, P Cubero, Bros, A Carrillo, Gómez, J, de Dios Molina Martín, J L Carrasco, Perera, M C, Averbach, E Goenaga, Palancares, M T, Gallego de Dios, C Fernández, Rojo, S Sánchez, Iglesias, M I Rubio, Merino, N Prieto, Mestre, A Pérez, Urdaniz, J M Martínez, Sánchez, R Gordo, Seco, J Franco, Muñoz, M Mateos, Agut, M L Blanco, Lozano, F Martín, Herguedas, A Torcal, Pena, J Vicente, García, A Varona, Martínez, O Sanz, Sanz Granado, M A Medina, Fernández, J M Moran, Canseco, P A Megia, López, M A Franco, Martín, J A Espina, Barrio, J Giner, Ubago, M Roca, Bennassar, J M Olivares, Díez, J L Hernandez, Fleta, F Porras, Fortes, C Arango, López, O, Medina, D Figuera, Alvarez, J M Peña, Roca, G Rubio, Valladolid, J A Furquet, Tavera, J A, García-Castrillon Sales, I Batalla, Llordes, C Anchuistegui, Melgarejo, F, Cañas de la Paz, V Vallés, Callol, M Bousoño, García, J Bobes, García, F J Vaz, Leal, E Cáceres, Corrales, E Sánchez, Iglesias, M A Carreiras, Gómez, G García, Serrano, E G Román, Chillarón, F J Samino, Aguado, J J Molina, Castillo, A González, González, J Gallardo, Vázquez, M Bolivar, Peralvarez, M Rios, Diaz, M Ybarzabal, Mesa, F J Acosta, Artiles, M Ajoy, Chao, P, del Rosario Santana, M A García, Escudero, M Molla, Berenguer, J M Bonete, Llacer, J A Juan, Berna, J Barragán, Ortiz, L Tost, Pardell, C, Hernández-Alvarez de Sotomayor, M R Cejas, Méndez, R Cabrera, Garate, B Díaz, Múgica, M Caballero, González, J Pujol, Domingo, C Sáez, Navarro, G Selva, Vera, M A, Cuquerella, J Lonjedo, Monzo, P Cervera, Boada, M F Martín, Pérez, E Carrasco, Parrado, J J Yañez, Sánchez, J Calvo, Fernández |
| Rok vydání: |
2008 |
| Předmět: |
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| Zdroj: |
European psychiatry : the journal of the Association of European Psychiatrists. 24(5) |
| ISSN: |
0924-9338 |
| Popis: |
BackgroundThe electronic Schizophrenia Treatment Adherence Registry (e-STAR) is a prospective, observational study of patients with schizophrenia designed to evaluate long-term treatment outcomes in routine clinical practice.MethodsParameters were assessed at baseline and at 3 month intervals for 2 years in patients initiated on risperidone long-acting injection (RLAI) (n= 1345) or a new oral antipsychotic (AP) (n= 277; 35.7% and 36.5% on risperidone and olanzapine, respectively) in Spain. Hospitalization prior to therapy was assessed by a retrospective chart review.ResultsAt 24 months, treatment retention (81.8% for RLAI versus 63.4% for oral APs,p< 0.0001) and reduction in Clinical Global Impression Severity scores (−1.14 for RLAI versus −0.94 for APs,p= 0.0165) were significantly higher with RLAI. Compared to the pre-switch period, RLAI patients had greater reductions in the number (reduction of 0.37 stays per patient versus 0.2,p< 0.05) and days (18.74 versus 13.02,p< 0.01) of hospitalizations at 24 months than oral AP patients.ConclusionsThis 2 year, prospective, observational study showed that, compared to oral antipsychotics, RLAI was associated with better treatment retention, greater improvement in clinical symptoms and functioning, and greater reduction in hospital stays and days in hospital in patients with schizophrenia. Improved treatment adherence, increased efficacy and reduced hospitalization with RLAI offer the opportunity of substantial therapeutic improvement in schizophrenia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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