Biotechnological re-cycling of apple by-products: A reservoir model to produce a dietary supplement fortified with biogenic phenolic compounds
| Autor: | Alessio Da Ros, Raffaella Di Cagno, Pasquale Filannino, Ali Zein Alabiden Tlais, Marco Gobbetti, Olimpia Vincentini |
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| Rok vydání: | 2020 |
| Předmět: |
Saccharomyces cerevisiae
Dietary supplement Microbial metabolism Anti-Inflammatory Agents medicine.disease_cause 01 natural sciences Antioxidants Analytical Chemistry 0404 agricultural biotechnology Phenols Tandem Mass Spectrometry medicine Humans Food science Chromatography High Pressure Liquid biology Chemistry 010401 analytical chemistry Lactobacillus fabifermentans food and beverages 04 agricultural and veterinary sciences General Medicine biology.organism_classification 040401 food science 0104 chemical sciences Bioavailability Lactobacillus Oxidative Stress Batch Cell Culture Techniques Malus Dietary Supplements Fermentation Caco-2 Cells Reactive Oxygen Species Lactobacillus plantarum Oxidative stress Food Science |
| Zdroj: | Food chemistry. 336 |
| ISSN: | 1873-7072 |
| Popis: | This study is an example of apple by-products (AP) recycling through a designed fermentation by selected autochthonous Lactobacillus plantarum AFI5 and Lactobacillus fabifermentans ALI6 used singly or as binary cultures with the selected Saccharomyces cerevisiae AYI7. Compared to Raw-, Unstarted- and Chemically Acidified-AP, Fermented-AP promoted the highest levels of total and insoluble dietary fibers, DPPH scavenging capacity, and free phenolics. The binary culture of L. plantarum AFI5 and S. cerevisiae AYI7 had the best effect on the bioavailability phenolic compounds as resulted by the LC-MS/MS validated method. The accumulation of phenolic acids derivatives highlighted the microbial metabolism during AP fermentation. Bio-converted phenolics were likely responsible for the increased DPPH scavenging capacity. The potential health-promoting effects of Fermented-AP were highlighted using Caco-2 cells. With variations among single and binary cultures, fermented-AP counteracted the inflammatory processes and the effects of oxidative stress in Caco-2 cells, and preserved the integrity of tight junctions. |
| Databáze: | OpenAIRE |
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