Biphasic effect of extracts of Lithospermum ruderale on the uptake of 32P by testes and thyroids of cockerels

Autor: Marvin Carmack, Charles J. Kelley, Frank J. Zeller, W. R. Breneman
Rok vydání: 1975
Předmět:
Zdroj: Biochemical and Biophysical Research Communications. 67:1234-1241
ISSN: 0006-291X
DOI: 10.1016/0006-291x(75)90805-0
Popis: A polyphenolic fraction of the plant Lithospermum ruderale was injected into White Leghorn cockerels at various time intervals and the effect on testes and thyroids was measured by the uptake of 32P. The 32P uptake 8 hours after lithosperm2 injection was markedly depressed and 12 hours after administration was notably increased. It is suggested that the hypothalamic regulation of the testes and thyroids is altered by lithosperm interference of the hypothalamic feedback system and/or the binding of receptor sites in the two glands.
Databáze: OpenAIRE