Synthetic cannabinoid drug use as a cause or contributory cause of death
| Autor: | Erica Williams, Laura D. Knight, Rebecca Jufer Phipps, Iain M. McIntyre, Robert Stoppacher, James L. Caruso, Andrea L. Wiens, Lee Marie Tormos, Barry K. Logan, Laura M. Labay, Nikolas P. Lemos, Thomas P. Gilson |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent Heart Diseases Substance-Related Disorders Poison control Autopsy 01 natural sciences Designer Drugs Pathology and Forensic Medicine Coroner Forensic Toxicology Young Adult 03 medical and health sciences 0302 clinical medicine Cause of Death Injury prevention Synthetic cannabinoids medicine Humans 030216 legal & forensic medicine Intensive care medicine Forensic Pathology Cause of death Cardiopulmonary disease Cannabinoids business.industry 010401 analytical chemistry Medical examiner Delirium Middle Aged United States 0104 chemical sciences Wounds and Injuries Female business Law Coroners and Medical Examiners medicine.drug |
| Zdroj: | Forensic Science International. 260:31-39 |
| ISSN: | 0379-0738 |
| DOI: | 10.1016/j.forsciint.2015.12.046 |
| Popis: | Adverse effects associated with synthetic cannabinoid use include agitation, psychosis, seizures and cardiovascular effects, all which may result in a lethal outcome. We report the collection of data from 25 medical examiner and coroner cases where the presence of synthetic cannabinoids was analytically determined. Participating offices provided case history, investigative and relevant autopsy findings and toxicology results along with the cause and manner of death determination. This information, with the agency and cause and manner of death determinations blinded, was sent to participants. Participants offered their opinions regarding the likely contribution of the toxicology findings to cause and manner of death. The results show that some deaths are being attributed to synthetic cannabinoids, with the highest risk areas being behavioral toxicity resulting in excited delirium, trauma or accidents and as contributing factors in subjects with pre-existing cardiopulmonary disease. While insufficient information exists to correlate blood synthetic cannabinoid concentrations to effect, in the absence of other reasonable causes, the drugs should be considered as a cause or contributory cause of death based on history and circumstances with supporting toxicological data. |
| Databáze: | OpenAIRE |
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