Artificial Egg Activation Using Calcium Ionophore

Autor:	Ahmed Khaled Tawfik Attia, Cara Nicholson, Sarah Martins da Silva
Rok vydání:	2021
Předmět:	Male Calcium Ionophores Endocrinology Reproductive Medicine Semen Fertilization Physiology (medical) Endocrinology Diabetes and Metabolism Oocytes Humans Obstetrics and Gynecology Sperm Injections Intracytoplasmic
Zdroj:	Seminars in Reproductive Medicine. 39:e5-e11
ISSN:	1526-4564 1526-8004
DOI:	10.1055/s-0041-1742171
Popis:	Artificial oocyte activation, most commonly using calcium ionophore, is a treatment add-on utilized to avoid recurrence of abnormally low or total failed fertilization following in vitro fertilization/intracytoplasmic sperm injection. It aims to modify defective physiological processes, specifically calcium-mediated cell signaling that are critical to events required for fertilization. Routine application of artificial oocyte activation is neither required nor recommended; however, it represents an invaluable intervention for a subgroup of patients affected by sperm-related oocyte activation deficiency.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44be0dda6c688558922deaff31b87ddd https://doi.org/10.1055/s-0041-1742171 Zobrazit plný text záznamu