Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
| Autor: | Ana Maria Coimbra Gaspar, Laura Branquinho do Nascimento, Aline Garcia Kozlowski, Regina Maria Bringel Martins, Ana Rita Coimbra Motta-Castro, Sheila Araújo Teles, Livia Melo Villar, Ágabo Macedo da Costa e Silva |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Microbiology (medical) lcsh:Arctic medicine. Tropical medicine Adolescent lcsh:RC955-962 viruses prevalence lcsh:QR1-502 Black People Enzyme-Linked Immunosorbent Assay Hepatitis A Antibodies lcsh:Microbiology Age Distribution Seroepidemiologic Studies hepatitis A virus parasitic diseases Humans Medicine Child Afro-Brazilian Aged Aged 80 and over business.industry Infant virus diseases Hepatitis A Middle Aged Virology digestive system diseases Hepatitis a virus Vaccination Child Preschool Female business Brazil Demography |
| Zdroj: | Memórias do Instituto Oswaldo Cruz., Vol 102, Iss 1, Pp 121-123 (2007) |
| ISSN: | 0074-0276 |
| DOI: | 10.1590/s0074-02762007000100021 |
| Popis: | To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6% (95% CI: 72.7-78.3), ranging from 55.4 to 97.3%, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8% in the age 0-5 age group to 96.6% in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|