Neuroblastoma presenting with the nephrotic syndrome
| Autor: | Tsuyoshi Maruyama, Shin Matsuda, Kisaku Satomura, Han-Long Zheng |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Male
Pathology medicine.medical_specialty Nephrotic Syndrome Inferior vena cava Neuroblastoma Membranous nephropathy medicine Humans Retroperitoneal Neoplasms business.industry Glomerular basement membrane General Medicine medicine.disease Thrombosis Radiography Stenosis medicine.anatomical_structure medicine.vein Child Preschool Pediatrics Perinatology and Child Health Surgery Thickening business Nephrotic syndrome |
| Zdroj: | Journal of Pediatric Surgery. 14:414-419 |
| ISSN: | 0022-3468 |
| DOI: | 10.1016/s0022-3468(79)80003-2 |
| Popis: | A case of neuroblastoma in a 4-yr-old boy presenting with the nephrotic syndrome is reported. Neither thrombosis nor stenosis of the renal veins and the inferior vena cava was present. Electron microscopy revealed lumps of subepithelial deposits as well as thickening and tortuosity of the glomerular basement membrane compatible with membranous nephropathy. It is postulated that deposition of neuroblastoma-associated immune complexes on the glomerular basement membrane-was responsible for the development of the nephrotic syndrome in this patient. Five pediatric cases of nephrotic syndrome associated with extrarenal neoplasia were collected from the world literature and are briefly discussed. |
| Databáze: | OpenAIRE |
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