Secondary Hemophagocytic Lymphohistiocytosis in Post-COVID-19 Patients: A Report of Two Cases
| Autor: | Biswajit Dey, Jaya Mishra, Devina Laishram, Pranjal Kalita, Bhupen Barman, Himesh Barman |
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| Rok vydání: | 2021 |
| Předmět: |
Secondary Hemophagocytic Lymphohistiocytosis
Hemophagocytic lymphohistiocytosis bone marrow Coronavirus disease 2019 (COVID-19) business.industry fungi General Engineering Infectious Disease Hematology Disease secondary hemophagocytic lymphohistiocytosis medicine.disease Virus Serology immune system sars-cov-2 medicine.anatomical_structure Immune system covid-19 Immunology medicine Bone marrow business |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.17328 |
| Popis: | Hemophagocytic lymphohistiocytosis (HLH) is a disease that can affect both children and adults. HLH can be categorized as primary or secondary. Secondary HLH (sHLH) may be secondary to various viral infections. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection is a pandemic with multi-system involvement. HLH in COVID-19 positive patients is a recognized entity. However, in post-COVID-19 patients who have recovered and are negative by serological tests and reverse transcription-polymerase chain reaction test may present with sHLH due to dysregulation of the immune system. We highlight this unusual finding of post-COVID-19 sHLH in two cases, who were diagnosed by the new revised H-score. |
| Databáze: | OpenAIRE |
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