Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide
| Autor: | Fatih Durmusoglu, Mick van Trotsenburg, Irene Lambrinoudaki, Dimitrios G. Goulis, Antonio Cano, Patrice Lopes, Johannes Bitzer, Amos Pines, Iuliana Ceausu, Margaret Rees, Peter Chedraui, Ludwig Kiesel, Angelica Lindén Hirschberg, Risto Erkkola |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Non-Hormonal Preparations
medicine.medical_specialty Chronic condition medicine.drug_class medicine.medical_treatment Urinary system Vaginal Diseases Urinary incontinence Vulvovaginal atrophy General Biochemistry Genetics and Molecular Biology Vulvovaginal Atrophy 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine medicine Humans Endocrine system 030212 general & internal medicine Expert Testimony 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology Estrogens Postmenopause Topical Estrogens Administration Intravaginal Estrogen Practice Guidelines as Topic Quality of Life Female Vulvar Diseases Atrophy medicine.symptom business Adjuvant |
| Zdroj: | Maturitas. 148:55-61 |
| ISSN: | 0378-5122 |
| Popis: | Introduction: Vulvovaginal atrophy (VVA) is a chronic condition caused by estrogen deficiency. It affects around 50% of postmenopausal women, reducing their general and sexual quality of life as well as the quality of their personal relationships. Aim: The aim of this clinical guide is to set out an individualized approach to the management of VVA with topical estrogens and non-hormonal preparations. Materials and methods: Literature review and consensus of expert opinion. Summary recommendations: An individualized approach is required for the management of VVA. Topical low-dose estrogens are effective and also alleviate urinary incontinence and prevent recurrent urinary tract infections. Women should not be denied long-term use of topical estrogens as long as they feel that this treatment is of benefit to them, because the safety data are reassuring. Non-hormonal preparations (lubricants and moisturizers) should be the first-line treatment for VVA in women taking adjuvant endocrine therapies for cancers considered to be hormone-dependent. They can be used over the long term. Sistema de Investigacion y Desarrollo (SINDE) ; Vice-Rectorado de Investigacion & Postgrado (VRIP) of the Universidad Catolica de Santiago de Guayaquil, Guayaquil, Ecuador |
| Databáze: | OpenAIRE |
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