Structures of the dienoic lactones of horse sebum
| Autor: | Philip W. Wertz, Donald T. Downing, Sabin W. Colton Vi, Marc L. Frost |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Sebaceous gland
Fatty acid biosynthesis Double bond Physiology Stereochemistry Molecular Conformation Biology Biochemistry Exocrine secretion Lactones Isomerism medicine Animals Horses Molecular Biology Skin chemistry.chemical_classification Endoplasmic reticulum Horse General Medicine Sebum medicine.anatomical_structure chemistry Fatty Acids Unsaturated Lactone |
| Zdroj: | Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 78:549-552 |
| ISSN: | 0305-0491 |
| DOI: | 10.1016/0305-0491(84)90095-6 |
| Popis: | 1. 1. The C 34 , C 36 , and C 38 dienoic ω-lactones were isolated from sebum of the horse ( Equus caballus ) and the double bond positions were determined by stepwise chemical dissection and analysis of the fragments. 2. 2. The structures found could be formed by Δ9-desaturation at the C 18 -stage of fatty acid biosynthesis followed by a second Δ9-desaturation when the chains reached C 24 , C 26 , C 28 , C 30 , or C 32 and then addition of one to seven 2-carbon units. 3. 3. These findings provide insight into the dimensions and organization of the endoplasmic reticulum in cells of the sebaceous glands. |
| Databáze: | OpenAIRE |
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