Cutaneous lymphoblastic lymphoma with pre-B markers

Autor: MP Link, M Roper, RF Dorfman, WM Crist, MD Cooper, R Levy
Rok vydání: 1983
Předmět:
Zdroj: Blood. 61(5)
ISSN: 0006-4971
Popis: Two children with cutaneous convoluted lymphoblastic lymphoma are reported. Malignant cells from both patients contained cytoplasmic Mu heavy chains characteristic of pre-B-cells and expressed CALLA and la antigens as well. Most cases of convoluted lymphoblastic lymphoma are T- cell-derived neoplasms. The non-T, non-B phenotype found in these two children demonstrates that histology does not necessarily predict immunophenotype. The association of the pre-B phenotype with cutaneous lymphoma has not been previously reported, but may represent a unique clinical-histopathologic-immunologic entity that occurs in young children.
Databáze: OpenAIRE