Effect of routine prenatal supplementation on vitamin concentrations in maternal serum and breast milk
| Autor: | Cristiane Santos Sânzio Gurgel, Roberto Dimenstein, Larisa Alves de Araújo Pereira, Larisse Rayanne Miranda de Melo, Mayara Adja da Silva Souza, Poliana Araújo de Brito, Aldiane de Assis Costa |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
0301 basic medicine Vitamin medicine.medical_specialty Endocrinology Diabetes and Metabolism Nutritional Status Physiology 030209 endocrinology & metabolism Breast milk Severity of Illness Index Dietary vitamin Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pregnancy Internal medicine Prevalence Humans Medicine Vitamin A Retrospective Studies 030109 nutrition & dietetics Nutrition and Dietetics Milk Human Vitamin A Deficiency business.industry Colostrum Postpartum Period Retinol food and beverages Maternal Nutritional Physiological Phenomena Vitamins beta Carotene medicine.disease Vitamin A deficiency Cross-Sectional Studies Endocrinology chemistry Dietary Supplements Female business Multivitamin Brazil |
| Zdroj: | Nutrition. 33:261-265 |
| ISSN: | 0899-9007 |
| DOI: | 10.1016/j.nut.2016.06.015 |
| Popis: | The aim of the present study was to assess the effect of multivitamin supplements and their different vitamin A sources on retinol concentrations in serum and colostrum milk of postpartum women.This was a retrospective cross-sectional study composed of healthy postpartum women attending two Brazilian private maternity wards (N = 100). According to the type of multivitamin taken during pregnancy, the women were assigned to one of four groups: control group (CG; n = 25), formulation 1 (F1; n = 25), formulation 2 (F2; n = 25), and formulation 3 (F3; n = 25). Blood and colostrum samples were collected under fasting conditions and retinol was analyzed by high-performance liquid chromatography. Dietary vitamin A was assessed using a food frequency questionnaire. Retinol concentrations20 μg/dL (0.70 μmol/L) in serum and60 μg/dL (2.10 μmol/L) in colostrum were considered indicative of vitamin A deficiency.Of women in the control group, 12% (n = 3) presented serum retinol levels below the cut-off value for adequacy; this was not observed in the supplemented groups. Evaluating the retinol content in breast milk, supplemented groups F1 and F3 presented 4% (n = 1) of inadequacy cases, whereas F2 presented 40% (n = 10). The concentrations found in the F2 and F3 groups were statistically different (P 0.05).The use of multivitamin supplements containing vitamin A during pregnancy prevents vitamin A deficiency regardless of the source administered. In breast milk, supplementation with β-carotene provided a lower concentration of vitamin A compared with retinol. |
| Databáze: | OpenAIRE |
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