Recurrence of progressive multifocal leukoencephalopathy despite immune recovery in two HIV seropositive individuals

Autor: Sarah E Turbett, Adrienne Morey, Michael Rodriguez, Igor J. Koralnik, Bruce J. Brew, Shruti P. Agnihotri, Matthew Gutman, Kate M. Crossley, Leon Patrick McNally, Joga Chaganti, Nagagopal Venna
Jazyk: angličtina
Předmět:
Zdroj: Journal of Neurovirology
ISSN: 1355-0284
DOI: 10.1007/s13365-015-0419-y
Popis: We present two cases of recurrent progressive multifocal leukoencephalopathy (PML) in patients with long standing virally suppressed human immunodeficiency virus (HIV) and normal CD4+ T cell count who were taking stable regimens of highly active antiretroviral therapy (HAART). This has significant implications for other patients with a past history of PML, not just those with HIV but also those on medications such as natalizumab or fumarates.
Databáze: OpenAIRE