Interleukin-10 production at the early stage of infection with foot-and-mouth disease virus related to the likelihood of persistent infection in cattle
| Autor: | John B. Bashiruddin, Claudia Doel, Zhidong Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
General Veterinary
Foot-and-mouth disease [SDV]Life Sciences [q-bio] Short Report Cattle Diseases Disease Biology medicine.disease biology.organism_classification veterinary(all) Virology Virus Interleukin-10 Persistence (computer science) Interleukin 10 Foot-and-Mouth Disease Virus Foot-and-Mouth Disease Immunology medicine Bacteriology Animals Cattle Interferons Foot-and-mouth disease virus |
| Zdroj: | Veterinary Research Veterinary Research, BioMed Central, 2015, 46 (1), pp.132. ⟨10.1186/s13567-015-0276-y⟩ |
| ISSN: | 0928-4249 1297-9716 |
| DOI: | 10.1186/s13567-015-0276-y⟩ |
| Popis: | International audience; AbstractThe factors leading to persistent infection of foot-and-mouth disease (FMD) virus in ruminants are not well defined. This paper provides evidence of the presence of interleukin-10 (IL-10) early in the course of infection (1–4 days) as a factor in the development of persistence of FMD virus in cattle. Results showed that serum IL-10 in carrier cattle infected with FMD virus type O (n = 4) was detected and peaked at 1 or 2 days post infection and rapidly declined thereafter. In contract, serum IL-10 levels in non-carrier cattle (n = 21) were very low or undetectable during the same period. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink