The new diagnostic criteria for myelodysplasia-related acute myeloid leukemia is useful for predicting clinical outcome: comparison of the 4th and 5th World Health Organization classifications

Autor: Hee Sue Park, Hee Kyung Kim, Hong-sik Kim, Yaewon Yang, Hye Sook Han, Ki Hyeong Lee, Bo Ra Son, Jihyun Kwon
Rok vydání: 2022
Předmět:
Zdroj: Annals of Hematology. 101:2645-2654
ISSN: 1432-0584
0939-5555
Popis: Mutations in myelodysplasia-related (MR) genes, rather than morphological features, have been included in the diagnostic criteria of the new 5th World Health Organization (WHO) classification for myelodysplastic syndrome (MDS)-associated acute myeloid leukemia (AML). This study compares the clinical relevance of the new criteria with those of the previous version. In a cohort of 135 patients with newly diagnosed AML, the MDS-related AML patients were classified according to the 5th and 4th edition of the WHO classification (AML, myelodysplasia-related [AML-MR
Databáze: OpenAIRE
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