Malignant rhabdoid tumor: Cyto-histologic correlation and immunohistochemical characterization of a rare pediatric malignancy and its differential diagnoses

Autor:	Allison L, Kerper, Anna-Lee, Clarke-Brodber, Sounak, Gupta, Kirsten M, Whalen, Recep, Nigdelioglu, Jennifer M, Boland, David J, Schembri Wismayer, Jorge, Torres-Mora, Marco R, Mejia Acevedo, Vineeth, Sudhindran, Charles D, Sturgis
Rok vydání:	2022
Předmět:	Diagnosis Differential Biomarkers Tumor Humans SMARCB1 Protein General Medicine Child Immunohistochemistry Kidney Neoplasms Rhabdoid Tumor Pathology and Forensic Medicine
Zdroj:	Annals of Diagnostic Pathology. 60:152014
ISSN:	1092-9134
DOI:	10.1016/j.anndiagpath.2022.152014
Popis:	Malignant rhabdoid tumor of the kidney (MRTK) is a rare aggressive pediatric renal tumor which can be diagnosed via fine-needle aspiration (FNA) cytology and core biopsy. The diagnosis of MRTK is challenging, and requires morphologic, immunohistochemical and clinical correlation to distinguish it from other entities. The differential diagnosis includes Wilms tumor, desmoplastic small round cell tumor, rhabdomyosarcoma, synovial sarcoma, renal medullary carcinoma, and epithelioid sarcoma. Here we describe a case of MRTK diagnosed on renal cytology and core biopsy with immunohistochemistry and follow by nephrectomy with gross and morphologic findings.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4485495dd2e61051522a3f8bccd26bd5 https://doi.org/10.1016/j.anndiagpath.2022.152014 Zobrazit plný text záznamu Full Text from ScienceDirect