Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells
| Autor: | Ya. D. Anfinogenova, Medvedev Ma, Leonid V. Kapilevich, Panov Aa, Baskakov Mb, A. G. Popov, Yu. L. Borodin, I. V. Kovalev |
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| Rok vydání: | 2000 |
| Předmět: |
Nitroprusside
Contraction (grammar) Membrane permeability Stereochemistry Chemistry Vasodilator Agents Guinea Pigs Uterus Muscle Smooth General Medicine General Biochemistry Genetics and Molecular Biology Sucrose gap Nitroglycerin Smooth muscle Nitro Biophysics medicine Electromechanical coupling Animals Female Sodium nitroprusside Muscle Contraction medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 129:455-457 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca(2+) membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles. |
| Databáze: | OpenAIRE |
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