Efficacy of autologous platelet‐rich plasma in the treatment of vitiligo: A 10‐patient prospective study

Autor: Mariem Rekik, Madiha Mseddi, Nadine Kammoun, Khadija Sellami, Hamida Turki
Rok vydání: 2022
Předmět:
Zdroj: Journal of Cosmetic Dermatology. 21:4225-4233
ISSN: 1473-2165
1473-2130
DOI: 10.1111/jocd.15050
Popis: Vitiligo is an autoimmune disorder characterized by loss of epidermal melanocytes. It has cosmetic and psychosocial impact. The objective of this paper is to evaluate the interest of platelet-rich-plasma in the treatment of vitiligo.We conducted a prospective study between January 2019 and September 2021.Our descriptive study included 10 patients followed-up for vitiligo refractory to conventional therapies. The mean age was 36.2 years. Sex ratio was 0.25. Prior to platelet-rich-plasma treatment, vitiligo was stable in all cases. The mean number of platelet-rich-plasma sessions received by our patients was 2.6 (1-6). A visible improvement of lesions was obtained after a mean of 1.5 sessions. 40% of patients had obtained repigmentation of more than 50% for at least one lesion. An improvement of more than 75% (grade 4) was noted in 2 cases after a mean duration of 5.5 sessions. 40% of patients had obtained repigmentation of more than 50% for at least one lesion. A percentage of improvement between 50 and 74% (grade 3) was obtained for 2 patients. Four patients had an improvement of less than 25% (grade 1) after a mean of 1.75 sessions. There was no recurrence of depigmentation after a mean follow-up of 6 months (1 to 24 months).Our series proves the benefit of platelet-rich-plasma in the treatment of vitiligo. It is a safe and promising option for stable lesions in different body sites with few side effects.
Databáze: OpenAIRE
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