Realizing Metal-Free Carbene-Catalyzed Carbonylation Reactions with CO
| Autor: | Max M. Hansmann, Eder Tomás-Mendivil, Jesse L Peltier, Rodolphe Jazzar, Daniel R. Tolentino, Guy Bertrand |
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| Přispěvatelé: | University of California [San Diego] (UC San Diego), University of California |
| Rok vydání: | 2020 |
| Předmět: |
Chemical transformation
Chemistry [CHIM.ORGA]Chemical Sciences/Organic chemistry General Chemistry [CHIM.CATA]Chemical Sciences/Catalysis 010402 general chemistry 01 natural sciences Biochemistry Chemical reaction Combinatorial chemistry Catalysis 0104 chemical sciences 3. Good health chemistry.chemical_compound Colloid and Surface Chemistry Organocatalysis [CHIM]Chemical Sciences Singlet state Carbonylation Carbene Carbon monoxide |
| Zdroj: | Journal of the American Chemical Society Journal of the American Chemical Society, American Chemical Society, 2020, 142 (43), pp.18336-18340. ⟨10.1021/jacs.0c09938⟩ |
| ISSN: | 1520-5126 0002-7863 |
| Popis: | International audience; Many organic and main group compounds, usually acids or bases, can accelerate chemical reactions when used in substoichiometric quantities, a process known as organocatalysis. In marked contrast, very few of these compounds are able to activate carbon monoxide and, until now, none of them catalyze its chemical transformation, a classical task for transition metals. Herein, we report that a stable singlet ambiphilic carbene activates CO and catalytically promotes the carbonylation of an ortho-quinone into a cyclic carbonate. These findings pave the way for the discovery of metal-free catalyzed carbonylation reactions. |
| Databáze: | OpenAIRE |
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