Relationship between glycemic control and coronary artery disease severity, prevalence and plaque characteristics by computed tomography coronary angiography in asymptomatic type 2 diabetic patients

Autor: Mateus G Fahel, Carlos H Rassi, Bernardo Léo Wajchenberg, A. C. Lerario, Carlos A. Tavares, Carlos E. Rochitte
Rok vydání: 2016
Předmět:
Blood Glucose
Male
endocrine system diseases
Computed Tomography Angiography
Coronary Artery Disease
030204 cardiovascular system & hematology
Coronary Angiography
Severity of Illness Index
Coronary artery disease
0302 clinical medicine
Risk Factors
Prevalence
Prospective Studies
Prospective cohort study
Computed tomography angiography
medicine.diagnostic_test
Middle Aged
Prognosis
Coronary Vessels
Plaque
Atherosclerotic
Cardiology
Female
medicine.symptom
Cardiology and Cardiovascular Medicine
Brazil
Adult
Acute coronary syndrome
medicine.medical_specialty
030209 endocrinology & metabolism
Diabetic angiopathy
Vascular Remodeling
Culprit
Asymptomatic
03 medical and health sciences
Predictive Value of Tests
Internal medicine
Multidetector Computed Tomography
medicine
Humans
Radiology
Nuclear Medicine and imaging
Vascular Calcification
Asymptomatic Diseases
Aged
Glycated Hemoglobin
business.industry
nutritional and metabolic diseases
medicine.disease
Diabetes Mellitus
Type 2
business
Biomarkers
Diabetic Angiopathies
Zdroj: The international journal of cardiovascular imaging. 32(10)
ISSN: 1875-8312
Popis: Evaluate whether glycemic control in type 2 diabetes (DM2) asymptomatic for coronary artery disease (CAD) affects not only the presence and magnitude of CAD but also the characteristics of plaque vulnerability using multidetector row computed coronary tomography (MDCT). Acute coronary syndrome (ACS) is frequently observed in asymptomatic DM2 patients. Positive vessel remodeling (PR) and low-attenuation plaques (LAP) identified by MDCT have been demonstrated to be characteristics of subsequent culprit lesions of ACS. However, little is known regarding plaque characteristics in asymptomatic diabetic patients and their relationship with glycemic control. Ninety asymptomatic DM2 patients, aged 40-65 years old, underwent MDCT. The presence of atherosclerotic obstruction, defined as coronary stenosis ≥50 %, and plaque characteristics were compared between two groups of patients with A1c
Databáze: OpenAIRE
Externí odkaz: