Oocyte cryopreservation for future fertility: comparison of ovarian response between cancer and non-cancer patients
| Autor: | João Pedro Junqueira Caetano, Erica Becker de Sousa Xavier, Janaína de Souza Guedes, Ricardo Mello Marinho, Ana Luisa Menezes Campos, Camila Cruz de Moraes, Victoria Furquim Werneck Marinho |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty fertility preservation oncofertility Cryopreservation Breast cancer Ovulation Induction Neoplasms medicine Humans cancer Fertility preservation Retrospective Studies Oncofertility Gynecology business.industry Incidence (epidemiology) Ovary Cancer Retrospective cohort study Oocyte cryopreservation medicine.disease Oocytes Female Original Article business |
| Zdroj: | JBRA Assisted Reproduction |
| ISSN: | 1518-0557 |
| DOI: | 10.5935/1518-0557.20190010 |
| Popis: | Objective This study aimed to assess whether a diagnosis of cancer interferes with ovarian function prior to the treatment of the disease. Methods This observational retrospective study used data from medical records of ovarian stimulation cycles performed for purposes of oocyte cryopreservation. Results The included patients had a mean age of 35.13±3.72 years and 51.6% of them were aged between 36 and 40 years. More than half of the patients (57.6%) were single and 82.1% had a normal body mass index (BMI). Most women had not become pregnant (85.5%) or had babies (95.1%) or miscarriages (89.6%) prior to cryopreservation. The mean number of oocytes obtained from non-cancer patients was 11.4±8, while for cancer patients the number was 13.8±9. The mean number of frozen mature oocytes was 9.7±7 for the non-cancer group and 11.2±7.2 for the cancer group. The majority (63.1%) of the patients had up to 10 oocytes frozen per cycle. Breast cancer had the highest incidence among the included patients. There was no significant difference in ovarian response between patients with different types of cancer. Conclusion The number of harvested and frozen oocytes from cancer and non-cancer patients indicated that in the two groups response to ovarian stimulation was similar. |
| Databáze: | OpenAIRE |
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