Patterns of chronic hepatitis B in Central Italy: a cross-sectional study
| Autor: | Piccolo, P., Lenci, I., Telesca, C., Di Paolo, D., Bandiera, F., De Melia, L., Sorbello, O., Renier, G., Ricci, G. L., Nosotti, L., Romano, M., DE SANTIS, Adriano, Levrero, Massimo, Antonucci, G., Longo, M. A., Annicchiarico, B. E., Angelico, M., Furlan, Caterina, Free Network Investigators, For The Hep B. |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty hepatitis b virus Cross-sectional study hcv co-infection Emigrants and Immigrants Comorbidity hbv dna hdv co-infection inactive hbsag carrier medicine.disease_cause Hepatitis D Middle Aged Female Italy Humans Carrier State Prevalence Cross-Sectional Studies Hepatitis B Chronic Hepatitis C Internal medicine medicine Chronic Hepatitis B virus Hepatitis Settore MED/12 - Gastroenterologia business.industry Incidence (epidemiology) Public Health Environmental and Occupational Health virus diseases Hepatitis B medicine.disease digestive system diseases Immunology Coinfection business |
| Popis: | We investigated the patterns of chronic hepatitis B virus (HBV)-related disease in a large cohort of HBsAg-positive patients, in Central Italy, by collecting a screening form with demographic, clinical and laboratory data. Overall, 737 HBsAg-positive cases were included (70% male; median age 52 years): 30% were inactive HBsAg carriers, 51% had chronic hepatitis B (CHB) and 19% had HBV-related cirrhosis. Patients from non-European Union (EU) countries (n = 65) were significantly younger, had a higher prevalence of HBeAg-positive infection and hepatitis delta virus (HDV) co-infection than patients of Italian origin. Therefore, as immigration from non-EU countries continues to grow, we can expect a change in the landscape of HBV-related disease in our area. |
| Databáze: | OpenAIRE |
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