Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
| Autor: | Efstathia Ioannou, Constantinos Vagias, Vassilios Roussis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Stereochemistry
Metabolite Spectrum Analysis dolastanes structure elucidation Absolute configuration Pharmaceutical Science Biology Phaeophyta Article Azulenes Dilophus spiralis chemistry.chemical_compound chemistry lcsh:Biology (General) Drug Discovery Chemical conversion Organic chemistry Spectrum analysis Diterpenes Pharmacology Toxicology and Pharmaceutics (miscellaneous) lcsh:QH301-705.5 |
| Zdroj: | Marine Drugs Volume 11 Issue 4 Pages 1104-1112 Marine Drugs, Vol 11, Iss 4, Pp 1104-1112 (2013) |
| ISSN: | 1660-3397 |
| DOI: | 10.3390/md11041104 |
| Popis: | Three new dolastane diterpenes (1-3) and five previously reported perhydroazulenes were isolated from the organic extracts of the brown alga Dilophus spiralis. The structure elucidation and the assignment of the relative configurations of the isolated natural products were based on extensive analyses of their spectroscopic data, whereas the absolute configuration of metabolite 2 was determined through its chemical conversion to a previously isolated compound of known configuration. |
| Databáze: | OpenAIRE |
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