Comparison of the erythrocyte sedimentation rate measured in the eye casualty department by the Seditainer method with an automated system
| Autor: | A C Browning, Peter R. Hodgkins, A A Burbidge |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Systemic disease genetic structures Adolescent Point-of-Care Systems Eye casualty Giant Cell Arteritis Blood Sedimentation medicine Humans Aged Aged 80 and over medicine.diagnostic_test Vascular disease business.industry Middle Aged medicine.disease eye diseases humanities Ophthalmology Red blood cell Giant cell arteritis medicine.anatomical_structure Erythrocyte sedimentation rate Female Vasculitis business Emergency Service Hospital |
| Zdroj: | Eye (London, England). 13 |
| ISSN: | 0950-222X |
| Popis: | To compare a new automated system for the measurement of erythrocyte sedimentation rate (ESR) with the established manual Seditainer method.Two hundred and twelve patients undergoing investigation for giant cell arteritis or other systemic vasculitides had ESR measurements by both the established manual Seditainer and the new laboratory-based automated system. The results were compared by correlation coefficient and mean difference. The limits of agreement with confidence intervals were also calculated.Across the range of results from 1 to 120 mm/h, the correlation coefficient was 0.844. The automated method had a mean negative bias of -9.8 mm/h (95% confidence interval: -12.2 to -7.4 mm/h). The wide scatter of results produced limits of agreement (+/- 2 standard deviations) between the two methods of -45 to 26 mm/h. There were seven results that were underestimated by the automated system which were clinically significant.There is a wide degree of scatter between the two sets of results. The automated system has a negative bias when compared with the manual method. There is a propensity for the automated system to sporadically underestimate the true result, sometimes to a degree that is clinically significant. The authors therefore cannot recommend replacement of the manual Seditainer system at the present time. |
| Databáze: | OpenAIRE |
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