Supplementary Figures S1-S7 from Targeted Treatment of Metastatic Breast Cancer by PLK1 siRNA Delivered by an Antioxidant Nanoparticle Platform

Autor: Wassana Yantasee, Joe W. Gray, Thanapon Sangvanich, David J. Castro, Moataz Reda, Shenda Gu, Worapol Ngamcherdtrakul, Jingga Morry
Rok vydání: 2023
DOI: 10.1158/1535-7163.22508410.v1
Popis: Supplementary Figure S1: Mesoporous silica-based nanoconstruct for targeted delivery of siRNA; Supplementary Figure S2: Screening of siPLK1 by mRNA knockdown and viability; Supplementary Figure S3: ROS intensity and NOX1-5 mRNA levels of TNBC cell lines; Supplementary Figure S4: HER2 signaling in LM2-4luc+/H2N cells; Supplementary Figure S5: Representative whole body bioluminescent IVIS imaging of a mouse injected with cancer cells; Supplementary Figure S6: Representative images of lung nodes of mice from short-term study; Supplementary Figure S7: Representative images of the whole lung, H&E, and anti-human vimentin staining of mouse lungs from the long-term study.
Databáze: OpenAIRE