Relationship of Peripheral Arterial Compliance and Standard Cardiovascular Risk Factors

Autor: W. Virgil Brown, Karen Wade, Howard J. Willens, David M. Herrington, Steve Mallon, Karen Kesler, Warren W. Davis, Johan H. C. Reiber, Jeffrey K. Raines
Rok vydání: 2003
Předmět:
Zdroj: Vascular and Endovascular Surgery. 37:197-206
ISSN: 1938-9116
1538-5744
DOI: 10.1177/153857440303700307
Popis: Abnormalities of peripheral arterial compliance are clinically useful markers of atherosclerosis and risk of vascular events. Local peripheral arterial compliance can be easily and accurately assessed in the clinic by computer-controlled pulse volume recordings (air plethysmography). The purpose of this study was to investigate the relationship between clinical cardiovascular risk factors, a surrogate of atherosclerotic burden, and peripheral arterial compliance in the thigh and calf determined by quantification of local pulse volume recordings in patients undergoing coronary angiography. Peripheral arterial compliance in the thigh and calf was measured in 346 patients undergoing diagnostic cardiac catheterization at 4 centers. Demographic and cardiovascular risk factor data were collected, and their relationship to local arterial compliance examined using a new device that assesses maximal local arterial volume change in an extremity segment. Pulse volume recordings detected decreased local arterial compliance in the thigh associated with a history of hypertension (p< 0.0001), diabetes mellitus (p = 0.0001), and hyperlipidemia (p = 0.0007). In the calf, this arterial compliance measure was associated with a history of hypertension (p < 0.0001) and diabetes mellitus (p = 0.002). Females had lower arterial compliance than males in the thigh (p = 0.003) and calf (p
Databáze: OpenAIRE