Adenoid cystic carcinoma of the prostate: A case report with immunohistochemical and in situ hybridization staining for prostate-specific antigen
| Autor: | Takahiko Hachiya, Sadatsugu Minei, Hajime Ishida, Kiyoki Okada |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male PCA3 medicine.medical_specialty Pathology Adenoid cystic carcinoma Urology medicine.medical_treatment urologic and male genital diseases Prostate cancer Prostate medicine Humans In Situ Hybridization Urinary bladder medicine.diagnostic_test business.industry Prostatectomy Prostatic Neoplasms Rectal examination Prostate-Specific Antigen medicine.disease Carcinoma Adenoid Cystic Immunohistochemistry Prostate-specific antigen medicine.anatomical_structure business |
| Zdroj: | International Journal of Urology. 8:S41-S44 |
| ISSN: | 1442-2042 0919-8172 |
| DOI: | 10.1046/j.1442-2042.2001.00333.x |
| Popis: | A 43-year-old man with urinary outlet obstruction was referred to our hospital. A digital rectal examination revealed an elastic hard prostate. The serum prostate-specific antigen (PSA), serum prostatic acid phosphate and γ-seminoprotein levels were found to be within the normal range, and transrectal ultrasound sonography provided normal findings. The patient underwent a subcapsular prostatectomy under a diagnosis of benign prostatic hyperplasia. Histopathologically, the lesion was diagnosed as an adenoid cystic carcinoma of the prostate. Because a further examination revealed a pathologic extension into the urinary bladder, a radical cystoprostatectomy was performed. The expression of PSA protein and PSA mRNA was studied by means of immunohistochemistry and an in situ hybridization technique. The adenoid cystic carcinoma in the patient did not show any positive signs for PSA protein or PSA mRNA. |
| Databáze: | OpenAIRE |
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