Prevalence of Metabolic Syndrome Among the End-Stage Renal Disease Patients on Hemodialysis
| Autor: | Awwadh Abdulrahman Althobaiti, Walaa Abduraheem Abuharba, Ahmed A Alzaidi, Maryam Mutlaq Alharthi, Khaled A. Alswat, Khulod Alsaadi, Amaal Saeed Alkhaldi |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry medicine.medical_treatment General Medicine medicine.disease Comorbidity Metabolic syndrome Surgery End stage renal disease Peritoneal dialysis 03 medical and health sciences End-stage renal disease 030104 developmental biology Internal medicine medicine Original Article Hemodialysis business Body mass index Dialysis Kidney disease |
| Zdroj: | Journal of Clinical Medicine Research |
| ISSN: | 1918-3003 |
| Popis: | Background: Patients with metabolic syndrome (MetS) have a 2.6-fold greater risk of incident chronic kidney disease (CKD). The primary goal of this study was to assess the prevalence of MetS in patients with end-stage renal disease (ESRD) who are on hemodialysis (HD) and the impact of MetS presence on HD-related outcomes. Methods: This is a cross-sectional study conducted in the Dialysis Center, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia. It was conducted among ESRD patients that attended the Dialysis Center between August 2013 and September 2016. We excluded patients on peritoneal dialysis and those < 18 years old. We used the International Diabetes Federation (IDF) criteria to identify patients with MetS. Results: A total of 241 patients with ESRD on HD were found, with a mean age of 48.8 (SD 16) years, mean body mass index (BMI) of 25.6 (SD 8.7) kg/m 2 , and mean waist circumference (WC) of 92.0 (SD 23.5) cm. The mean duration of the HD was 69.3 (SD 65.6) months with arteriovenous fistula (AVF) as the most common access for HD. Of the patients, 38.2% had MetS. Compared to those without MetS, those with MetS were more likely to be older (P < 0.001), be female (P < 0.001), be married (P < 0.001), have higher BMI (P < 0.001), have larger WC (P < 0.001), have T2D and hypertension (HTN) (P < 0.001), have shorter HD duration (P < 0.001), have a longer duration since the AVF was placed (P = 0.026), and have high post-HD creatinine levels (P = 0.010) and were less likely to have adequate HD (P = 0.004) and have parathyroid hormone (PTH) at goal (P = 0.046). Conclusion: MetS is common among ESRD and MetS was associated with more comorbidity, worse anthropometric measures at baseline, and worse HD-related outcomes. The limitations were small sample size and single center. J Clin Med Res. 2017;9(8):687-694 doi: https://doi.org/10.14740/jocmr3064w |
| Databáze: | OpenAIRE |
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