Prognostic Value of Increased Mitral Valve Gradient After Transcatheter Edge-to-Edge Repair for Primary Mitral Regurgitation

Autor: Sung-Han Yoon, Moody Makar, Saibal Kar, Tarun Chakravarty, Luke Oakley, Navjot Sekhon, Keita Koseki, Yusuke Enta, Mamoo Nakamura, Michele Hamilton, Jignesh K. Patel, Siddharth Singh, Sabah Skaf, Robert J. Siegel, Jeroen J. Bax, Raj R. Makkar
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JACC: Cardiovascular Interventions, 15(9), 935-945. ELSEVIER SCIENCE INC
Popis: OBJECTIVES This study sought to evaluate the prognostic value of an increased mean mitral valve pressure gradient (MVG) in patients with primary mitral regurgitation (MR) after transcatheter edge-to-edge repair (TEER).BACKGROUND Conflicting data exist regarding impact of increased mean MVG on outcomes after TEER.METHODS This study included 419 patients with primary MR (mean age 80.6 +/- 10.4 years; 40.6% female) who underwent TEER. Patients were divided into quartiles (Qs) based on discharge echocardiographic mean MVG. Primary outcome was the composite endpoint of all-cause mortality and heart failure hospitalization. Secondary outcomes included all-cause mortality and the secondary composite endpoint of all-cause mortality, heart failure hospitalization, and mitral valve reintervention.RESULTS The median number of MitraClips used was 2 per patient. MR reduction
Databáze: OpenAIRE