Kaempferia parviflora ethanol extract improves self-assessed sexual health in men: a pilot study
| Autor: | Jowell Bolivar, Andrew G. Swick, Kira Schmid, Steven Hirsh, Richard A. Stein, Steven V. Joyal |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Sexual Behavior Population ved/biology.organism_classification_rank.species Psychological intervention Pilot Projects 03 medical and health sciences 0302 clinical medicine Erectile Dysfunction Zingiberaceae medicine Humans Medical prescription Adverse effect education Aged Reproductive health Kaempferia parviflora education.field_of_study 030219 obstetrics & reproductive medicine Plant Extracts business.industry ved/biology Penile Erection General Medicine Middle Aged medicine.disease Clinical trial Treatment Outcome Erectile dysfunction 030220 oncology & carcinogenesis Physical therapy Sexual Health business |
| Zdroj: | Journal of Integrative Medicine. 16:249-254 |
| ISSN: | 2095-4964 |
| Popis: | Background Sexual health positively correlates with overall wellbeing. Existing therapeutics to enhance male sexual health are limited by factors that include responsiveness, adherence and adverse effects. As the population ages, safe and effective interventions that preserve male sexual function are needed. Published research suggests that various preparations of Kaempferia parviflora, a plant in the Zingiberaceae (ginger) family, support cardiovascular health and may ameliorate erectile function. Objective The aim of this study was to examine the effects of KaempMax™, an ethanol extract of the K. parviflora rhizome, on erectile function in healthy middle-aged and older men. Design, setting, participants and interventions We conducted an open-label, one-arm study on 14 generally healthy males aged 50–68 years with self-reported mild erectile dysfunction, who were not using prescription treatments. Participants took 100 mg KaempMax™ daily for 30 days. Main outcome measures Evaluations were conducted at baseline and on the final study assessment. Primary efficacy analyses included the International Index of Erectile Function (IIEF); secondary efficacy analyses included the Global Assessment Question about erectile function. Results Thirteen participants completed the 30-day study. Supplementation with KaempMax™ resulted in statistically significant improvements in erectile function, intercourse satisfaction and total scores on the IIEF questionnaire. KaempMax™ was well tolerated and exhibited an excellent safety profile. Conclusion Our results suggest that KaempMax™ may improve erectile function in healthy middle-aged and older men. While the effects were not as pronounced as what might be seen with prescription medication, most participants found them satisfactory. Additional, longer and placebo-controlled clinical trials will be needed. Trial registration Clinicaltrials.gov identifier NCT03389867. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect