Using double pulsed-field gradient MRI to study tissue microstructure in traumatic brain injury (TBI)

Autor:	Elizabeth B. Hutchinson, Carlo Pierpaoli, Peter J. Basser, Lynne A. Holtzclaw, Sarah King, Alexandru V. Avram, Michal E. Komlosh, Margalit Haber, Dan Benjamini, Abhishek Desai
Rok vydání:	2018
Předmět:	Materials science Traumatic brain injury Anisotropic diffusion Diffuse axonal injury General Chemistry Condensed Matter Physics medicine.disease Microstructure Article 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Animal model medicine.anatomical_structure Nuclear magnetic resonance Mechanics of Materials medicine General Materials Science Axon Pulsed field gradient 030217 neurology & neurosurgery
Zdroj:	Microporous and Mesoporous Materials. 269:156-159
ISSN:	1387-1811
Popis:	Double pulsed-field gradient (dPFG) MRI is proposed as a new sensitive tool to detect and characterize tissue microstructure following diffuse axonal injury. In this study dPFG MRI was used to estimate apparent mean axon diameter in a diffuse axonal injury animal model and in healthy fixed mouse brain. Histological analysis was used to verify the presence of the injury detected by MRI.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443678cfddb26c97fd62b40b66472cb2 https://doi.org/10.1016/j.micromeso.2017.05.030 Zobrazit plný text záznamu Full Text from ScienceDirect