Supplementary Figure S5. Cell proliferation inhibition of cetuximab, FASN inhibitor (EGCG or C75) and the combination. from Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer

Autor: Teresa Puig, Alana L. Welm, Ariadna Sarrats, Ferran Pérez-Bueno, Glòria Oliveras, Gemma Viñas, Adriana Blancafort, David H. Lum, Sònia Palomeras, Ariadna Giró-Perafita
Rok vydání: 2023
Popis: (A) 231 and 231DXR and (B) HCC and HCCDXR cells were treated with doxorubicin (50-100-150nM) and C75 (20µM for HCC, HCCDXR; 40µM for 231, 231DXR) or the combination for 48h. (C) 231 and 231DXR and (D) HCC and HCCDXR cells were treated with doxorubicin (50-100-150nM), EGCG (100µM for 231, 231DXR; 120µM for HCC, HCCDXR) or the combination of both for 48h. Results shown are mean {plus minus} SEM. *(p < 0.05), **(p < 0.01) and ***(p < 0.001) indicate levels of statistically significance.
Databáze: OpenAIRE