Enantioselective Synthesis of Functionalized Fluorinated Cyclohexenones via Robinson Annulation Catalyzed by Primary−Secondary Diamines
| Autor: | Zhuo Chai, Changwu Zheng, Shizheng Zhu, Haifeng Cui, Ying-Quan Yang, Peng Li, Gang Zhao |
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| Rok vydání: | 2009 |
| Předmět: |
Models
Molecular Magnetic Resonance Spectroscopy Primary (chemistry) Hydrocarbons Fluorinated Cyclohexanones Organic Chemistry Enantioselective synthesis Stereoisomerism Diamines Chemical synthesis Catalysis Stereocenter chemistry.chemical_compound chemistry Diamine Robinson annulation Organic chemistry |
| Zdroj: | The Journal of Organic Chemistry. 75:117-122 |
| ISSN: | 1520-6904 0022-3263 |
| DOI: | 10.1021/jo902081w |
| Popis: | Primary-secondary diamine catalysts were used to catalyze the asymmetric Robinson annulation to synthesize multiply substituted fluorinated chiral cyclohexenones with two contiguous stereogenic centers, one of which is a fluorinated quaternary chiral center, with excellent enantioselectivities and diastereoselectivities in moderate to good yields. |
| Databáze: | OpenAIRE |
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