M91. Temporal Lobe Thinning and Verbal Learning in First-Degree Relatives of Individuals With Schizophrenia

Autor: Asarnow R, Fernandez
Rok vydání: 2017
Předmět:
Zdroj: Schizophrenia Bulletin. 43:S243-S244
ISSN: 1745-1701
0586-7614
DOI: 10.1093/schbul/sbx022.086
Popis: Background: Cortical thinning in frontal and temporal regions has been reported in individuals diagnosed with schizophrenia and, less consistently, among their unaffected first-degree relatives. Likewise, first-degree relatives demonstrate deficits in their neurocognitive performance relative to healthy controls, albeit attenuated compared to schizophrenia probands. Less is known about how cortical thinning relates to neurocognitive performance in these individuals. Given the robust nature of temporal structural abnormalities in schizophrenia, this study aimed to identify how temporal lobe density might relate to performance on verbal memory tasks in first-degree relatives.
Databáze: OpenAIRE