BiMM tree: a decision tree method for modeling clustered and longitudinal binary outcomes

Autor: Bethany J. Wolf, Constantine J. Karvellas, David G. Koch, Valerie Durkalski, Jaime L. Speiser, Dongjun Chung
Rok vydání: 2018
Předmět:
Zdroj: Commun Stat Simul Comput
ISSN: 1532-4141
0361-0918
DOI: 10.1080/03610918.2018.1490429
Popis: Clustered binary outcomes are frequently encountered in clinical research (e.g. longitudinal studies). Generalized linear mixed models (GLMMs) for clustered endpoints have challenges for some scenarios (e.g. data with multi-way interactions and nonlinear predictors unknown a priori). We develop an alternative, data-driven method called Binary Mixed Model (BiMM) tree, which combines decision tree and GLMM within a unified framework. Simulation studies show that BiMM tree achieves slightly higher or similar accuracy compared to standard methods. The method is applied to a real dataset from the Acute Liver Failure Study Group.
Databáze: OpenAIRE