Diffusion-weighted imaging of the brain in children with tuberous sclerosis complex: A comparative study
| Autor: | Mehmet Haydar Atalar, R. N. Sener |
|---|---|
| Přispěvatelé: | Atalar, M.H., Department of Radiology, Cumhuriyet University School of Medicine, Sivas, Turkey -- Şener, R.N., Department of Radiology, Ege University School of Medicine, Izmir, Turkey |
| Rok vydání: | 2015 |
| Předmět: |
Cortical tubers
medicine.medical_specialty medicine.diagnostic_test business.industry Brain Magnetic resonance imaging Inversion recovery medicine.disease Control subjects Tuberous sclerosis Tuberous sclerosis complex Pediatrics Perinatology and Child Health Apparent diffusion coefficient values medicine Effective diffusion coefficient Radiology Nuclear Medicine and imaging In patient Diffusion-weighted imaging Neurology (clinical) Radiology business Mri Diffusion MRI |
| Zdroj: | Journal of Pediatric Neuroradiology. :043-047 |
| ISSN: | 1309-6745 1309-6680 |
| Popis: | To evaluate diffusion imaging characteristics of parenchymal changes in patients with tuberous sclerosis complex (TSC) compared with those in control subjects. We reviewed magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) findings in six patients diagnosed with TSC. MRI examinations were performed in a 1.5 Tesla MRI unit using a transmit/receive coil with T1-weighted and T2-weighted spin-echo and fluid-attenuated inversion recovery sequences. DWI MRI was obtained using an echo-planar imaging sequence. Apparent diffusion coefficient (ADC) values were measured. In addition, five normal children were studied for comparison. ADC was higher in cortical tubers than in the corresponding cortical location of controls (p < 0.05). ADC values were higher in white-matter lesions and perilesional white matter than in the contralateral normal-appearing white matter of both patients and controls (p < 0.05). There were no differences for ADC values between the normal-appearing white matter of patients with TSC and control subjects. It appears that DWI MRI can be useful in the evaluation of parenchymal changes associated with TSC. © 2012 - IOS Press and the authors. Atalar, M.H.; Department of Radiology, Cumhuriyet University School of Medicine, Sivas, TR-58140, Turkey; email: mehmet5896@yahoo.com |
| Databáze: | OpenAIRE |
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