Use of phytopathogenic virus for peptide expression in plant system

Autor: Emanuele Silva de Sousa, Isaac Neto Goes da Silva, Bruno Bezerra da Silva, Lívia Maria Carlos Marques, Lia de Almeida Magalhães, Maria Izabel Florindo Guedes, Francisco Jarbas Santos de Sousa, Márcia Maria Mendes Marques, Lucelina da Silva Araújo
Rok vydání: 2014
Předmět:
Zdroj: BMC Proceedings
ISSN: 1753-6561
DOI: 10.1186/1753-6561-8-s4-p151
Popis: Background Some plant viruses have been used to express and / or car peptides from human and animal pathogens for diagnostic purposes or vaccine. This system has presented many advantages over traditional methods, especially with regard to cost and production of peptides free of pathogens [1]. In this context, the possibility of using these viruses in an effort to produce peptide vaccine candidates in veterinary medicine is presented as a very promising idea. Among the relevant diseases in veterinary medicine there iscaprine artritre encephalitis (CAE) virus infection caprine arthritis-encephalitis (CAEV). This virus infects goats worldwide causing arthritis, encephalitis, mastitis, progressive weight loss and mainly fall in production and consequently a major economic loss to producers [2]. This disease is silent and yet there is still no treatment nor vaccine, and the control accomplished by early diagnosis. Therefore, this study aimed to produce peptides CAEV using a plant system.
Databáze: OpenAIRE